Long-Term Studies Of COVID-19 Vaccines Hurt By Placebo Recipients Getting Immunized

Leyda Valentine, a research coordinator, takes blood from Lisa Taylor as she participates in a COVID-19 vaccination study at Research Centers of America in Hollywood, Fla., in August 2020.

Joe Raedle / Getty Images

Tens of thousands of people who volunteered to be in studies of the Pfizer-BioNTech and Moderna COVID-19 vaccines are still participating in follow-up research. But some key questions won’t be easily answered, because many people who had been in the placebo group have now opted to take the vaccine.

Even so, there’s valuable information to be had in the planned two-year follow-up studies. And that motivated Karen Mott, a 56-year-old job counselor who stuck with the continuing study.

“I’ve been taking prescription medicine for the last 25 years,” she says, referring to antiseizure drugs she takes. In order to show those drugs worked, people previously volunteered to take them when they were still experimental, “so I felt it was my way of giving back.”