COVID-19 Vaccine: Will It Protect Against New Variants And Do You Need A 2nd Dose?

Southern California recipients of a COVID-19 vaccine at a mass vaccination site in Disneyland’s parking lot in January. For strongest immunity, be sure to get both doses of the Pfizer or Moderna vaccine, says the CDC’s new head. She also says stretching the interval between shots to six weeks can be OK “in rare circumstances.”

Mario Tama / Getty Images

As the virus that causes COVID-19 continues its global attack, it has done what scientists predicted it would do — it’s given rise to new, slightly different strains. How significant some of those strains will be to the pandemic is now under intense study. Meanwhile, demand for the currently available vaccines is outstripping the early supply, and some scientists have sparked controversy by suggesting holding off on booster shots until more people have had their initial shots. That’s something the Centers for Disease Control and Prevention does not endorse — but the agency has extended the timing on the second dose a bit.

What does this all mean for you? Let’s start with the question of second doses.

Why do the manufacturers and CDC advise two doses of the Pfizer and Moderna vaccines?