Doctors Encouraged By Antibody Treatments For COVID-19

Nurse Janet Gilleran prepares to treat COVID-19 patient Mike Mokler with bamlanivimab, a monoclonal antibody drug from Eli Lilly, at the Respiratory Infection Clinic of Tufts Medical Center in Boston on Dec. 31, 2020.

Craig F. Walker / Boston Globe via Getty Images

Many doses of the monoclonal antibody drugs that treat mild to moderate COVID-19 are sitting unused around the country. There are logistical problems with providing these drugs and skepticism over whether they work. But two major health systems have had good success in deploying these medications, and they’re reporting hopeful results.

Monoclonal antibodies, manufactured by Regeneron and Eli Lilly, have been available since just before Thanksgiving. The Food and Drug Administration authorized them for emergency use after studies suggested that they reduced the risk of hospitalization among people at elevated risk. That includes people over 65 and those with underlying health conditions such as obesity.

The drugs are antibodies engineered to bind to the coronavirus so it can’t enter human cells. President Trump received a dose of the Regeneron product before it had been authorized for emergency use and his administration bought more than a million doses to distribute to hospitals around the country.